Frequency Dropout: Feature-Level Regularization via Randomized Filtering

Deep convolutional neural networks have shown remarkable performance on various computer vision tasks, and yet, they are susceptible to picking up spurious correlations from the training signal. So called `shortcuts' can occur during learning, for example, when there are specific frequencies present in the image data that correlate with the output predictions. Both high and low frequencies can be characteristic of the underlying noise distribution caused by the image acquisition rather than in relation to the task-relevant information about the image content. Models that learn features related to this characteristic noise will not generalize well to new data. In this work, we propose a simple yet effective training strategy, Frequency Dropout, to prevent convolutional neural networks from learning frequency-specific imaging features. We employ randomized filtering of feature maps during training which acts as a feature-level regularization. In this study, we consider common image processing filters such as Gaussian smoothing, Laplacian of Gaussian, and Gabor filtering. Our training strategy is model-agnostic and can be used for any computer vision task. We demonstrate the effectiveness of Frequency Dropout on a range of popular architectures and multiple tasks including image classification, domain adaptation, and semantic segmentation using both computer vision and medical imaging datasets. Our results suggest that the proposed approach does not only improve predictive accuracy but also improves robustness against domain shift.Comment: 15 page

Revisiting Distillation for Continual Learning on Visual Question Localized-Answering in Robotic Surgery

The visual-question localized-answering (VQLA) system can serve as a knowledgeable assistant in surgical education. Except for providing text-based answers, the VQLA system can highlight the interested region for better surgical scene understanding. However, deep neural networks (DNNs) suffer from catastrophic forgetting when learning new knowledge. Specifically, when DNNs learn on incremental classes or tasks, their performance on old tasks drops dramatically. Furthermore, due to medical data privacy and licensing issues, it is often difficult to access old data when updating continual learning (CL) models. Therefore, we develop a non-exemplar continual surgical VQLA framework, to explore and balance the rigidity-plasticity trade-off of DNNs in a sequential learning paradigm. We revisit the distillation loss in CL tasks, and propose rigidity-plasticity-aware distillation (RP-Dist) and self-calibrated heterogeneous distillation (SH-Dist) to preserve the old knowledge. The weight aligning (WA) technique is also integrated to adjust the weight bias between old and new tasks. We further establish a CL framework on three public surgical datasets in the context of surgical settings that consist of overlapping classes between old and new surgical VQLA tasks. With extensive experiments, we demonstrate that our proposed method excellently reconciles learning and forgetting on the continual surgical VQLA over conventional CL methods. Our code is publicly accessible.Comment: To appear in MICCAI 2023. Code availability: https://github.com/longbai1006/CS-VQL

Robustness Stress Testing in Medical Image Classification

Deep neural networks have shown impressive performance for image-based disease detection. Performance is commonly evaluated through clinical validation on independent test sets to demonstrate clinically acceptable accuracy. Reporting good performance metrics on test sets, however, is not always a sufficient indication of the generalizability and robustness of an algorithm. In particular, when the test data is drawn from the same distribution as the training data, the iid test set performance can be an unreliable estimate of the accuracy on new data. In this paper, we employ stress testing to assess model robustness and subgroup performance disparities in disease detection models. We design progressive stress testing using five different bidirectional and unidirectional image perturbations with six different severity levels. As a use case, we apply stress tests to measure the robustness of disease detection models for chest X-ray and skin lesion images, and demonstrate the importance of studying class and domain-specific model behaviour. Our experiments indicate that some models may yield more robust and equitable performance than others. We also find that pretraining characteristics play an important role in downstream robustness. We conclude that progressive stress testing is a viable and important tool and should become standard practice in the clinical validation of image-based disease detection models.Comment: 11 page

Angular Gap: Reducing the Uncertainty of Image Difficulty through Model Calibration

Curriculum learning needs example difficulty to proceed from easy to hard. However, the credibility of image difficulty is rarely investigated, which can seriously affect the effectiveness of curricula. In this work, we propose Angular Gap, a measure of difficulty based on the difference in angular distance between feature embeddings and class-weight embeddings built by hyperspherical learning. To ascertain difficulty estimation, we introduce class-wise model calibration, as a post-training technique, to the learnt hyperbolic space. This bridges the gap between probabilistic model calibration and angular distance estimation of hyperspherical learning. We show the superiority of our calibrated Angular Gap over recent difficulty metrics on CIFAR10-H and ImageNetV2. We further propose a curriculum based on Angular Gap for unsupervised domain adaptation that can translate from learning easy samples to mining hard samples. We combine this curriculum with a state-of-the-art self-training method, Cycle Self Training (CST). The proposed Curricular CST learns robust representations and outperforms recent baselines on Office31 and VisDA 2017

Co-Attention Gated Vision-Language Embedding for Visual Question Localized-Answering in Robotic Surgery

Medical students and junior surgeons often rely on senior surgeons and specialists to answer their questions when learning surgery. However, experts are often busy with clinical and academic work, and have little time to give guidance. Meanwhile, existing deep learning (DL)-based surgical Visual Question Answering (VQA) systems can only provide simple answers without the location of the answers. In addition, vision-language (ViL) embedding is still a less explored research in these kinds of tasks. Therefore, a surgical Visual Question Localized-Answering (VQLA) system would be helpful for medical students and junior surgeons to learn and understand from recorded surgical videos. We propose an end-to-end Transformer with Co-Attention gaTed Vision-Language (CAT-ViL) for VQLA in surgical scenarios, which does not require feature extraction through detection models. The CAT-ViL embedding module is designed to fuse heterogeneous features from visual and textual sources. The fused embedding will feed a standard Data-Efficient Image Transformer (DeiT) module, before the parallel classifier and detector for joint prediction. We conduct the experimental validation on public surgical videos from MICCAI EndoVis Challenge 2017 and 2018. The experimental results highlight the superior performance and robustness of our proposed model compared to the state-of-the-art approaches. Ablation studies further prove the outstanding performance of all the proposed components. The proposed method provides a promising solution for surgical scene understanding, and opens up a primary step in the Artificial Intelligence (AI)-based VQLA system for surgical training. Our code is publicly available.Comment: To appear in MICCAI 2023. Code availability: https://github.com/longbai1006/CAT-Vi

Generalizing Surgical Instruments Segmentation to Unseen Domains with One-to-Many Synthesis

Despite their impressive performance in various surgical scene understanding tasks, deep learning-based methods are frequently hindered from deploying to real-world surgical applications for various causes. Particularly, data collection, annotation, and domain shift in-between sites and patients are the most common obstacles. In this work, we mitigate data-related issues by efficiently leveraging minimal source images to generate synthetic surgical instrument segmentation datasets and achieve outstanding generalization performance on unseen real domains. Specifically, in our framework, only one background tissue image and at most three images of each foreground instrument are taken as the seed images. These source images are extensively transformed and employed to build up the foreground and background image pools, from which randomly sampled tissue and instrument images are composed with multiple blending techniques to generate new surgical scene images. Besides, we introduce hybrid training-time augmentations to diversify the training data further. Extensive evaluation on three real-world datasets, i.e., Endo2017, Endo2018, and RoboTool, demonstrates that our one-to-many synthetic surgical instruments datasets generation and segmentation framework can achieve encouraging performance compared with training with real data. Notably, on the RoboTool dataset, where a more significant domain gap exists, our framework shows its superiority of generalization by a considerable margin. We expect that our inspiring results will attract research attention to improving model generalization with data synthesizing.Comment: First two authors contributed equally. Accepted by IROS202

Confidence-Aware Paced-Curriculum Learning by Label Smoothing for Surgical Scene Understanding

Curriculum learning and self-paced learning are the training strategies that gradually feed the samples from easy to more complex. They have captivated increasing attention due to their excellent performance in robotic vision. Most recent works focus on designing curricula based on difficulty levels in input samples or smoothing the feature maps. However, smoothing labels to control the learning utility in a curriculum manner is still unexplored. In this work, we design a paced curriculum by label smoothing (P-CBLS) using paced learning with uniform label smoothing (ULS) for classification tasks and fuse uniform and spatially varying label smoothing (SVLS) for semantic segmentation tasks in a curriculum manner. In ULS and SVLS, a bigger smoothing factor value enforces a heavy smoothing penalty in the true label and limits learning less information. Therefore, we design the curriculum by label smoothing (CBLS). We set a bigger smoothing value at the beginning of training and gradually decreased it to zero to control the model learning utility from lower to higher. We also designed a confidence-aware pacing function and combined it with our CBLS to investigate the benefits of various curricula. The proposed techniques are validated on four robotic surgery datasets of multi-class, multi-label classification, captioning, and segmentation tasks. We also investigate the robustness of our method by corrupting validation data into different severity levels. Our extensive analysis shows that the proposed method improves prediction accuracy and robustness. The code is publicly available at https://github.com/XuMengyaAmy/P-CBLS. Note to Practitioners —The motivation of this article is to improve the performance and robustness of deep neural networks in safety-critical applications such as robotic surgery by controlling the learning ability of the model in a curriculum learning manner and allowing the model to imitate the cognitive process of humans and animals. The designed approaches do not add parameters that require additional computational resources

Curriculum-Based Augmented Fourier Domain Adaptation for Robust Medical Image Segmentation

Accurate and robust medical image segmentation is fundamental and crucial for enhancing the autonomy of computer-aided diagnosis and intervention systems. Medical data collection normally involves different scanners, protocols, and populations, making domain adaptation (DA) a highly demanding research field to alleviate model degradation in the deployment site. To preserve the model performance across multiple testing domains, this work proposes the Curriculum-based Augmented Fourier Domain Adaptation (Curri-AFDA) for robust medical image segmentation. In particular, our curriculum learning strategy is based on the causal relationship of a model under different levels of data shift in the deployment phase, where the higher the shift is, the harder to recognize the variance. Considering this, we progressively introduce more amplitude information from the target domain to the source domain in the frequency space during the curriculum-style training to smoothly schedule the semantic knowledge transfer in an easier-to-harder manner. Besides, we incorporate the training-time chained augmentation mixing to help expand the data distributions while preserving the domain-invariant semantics, which is beneficial for the acquired model to be more robust and generalize better to unseen domains. Extensive experiments on two segmentation tasks of Retina and Nuclei collected from multiple sites and scanners suggest that our proposed method yields superior adaptation and generalization performance. Meanwhile, our approach proves to be more robust under various corruption types and increasing severity levels. In addition, we show our method is also beneficial in the domain-adaptive classification task with skin lesion datasets. The code is available at https://github.com/lofrienger/Curri-AFDA. Note to Practitioners —Medical image segmentation is key to improving computer-assisted diagnosis and intervention autonomy. However, due to domain gaps between different medical sites, deep learning-based segmentation models frequently encounter performance degradation when deployed in a novel domain. Moreover, model robustness is also highly expected to mitigate the effects of data corruption. Considering all these demanding yet practical needs to automate medical applications and benefit healthcare, we propose the Curriculum-based Fourier Domain Adaptation (Curri-AFDA) for medical image segmentation. Extensive experiments on two segmentation tasks with cross-domain datasets show the consistent superiority of our method regarding adaptation and generalization on multiple testing domains and robustness against synthetic corrupted data. Besides, our approach is independent of image modalities because its efficacy does not rely on modality-specific characteristics. In addition, we demonstrate the benefit of our method for image classification besides segmentation in the ablation study. Therefore, our method can potentially be applied in many medical applications and yield improved performance. Future works may be extended by exploring the integration of curriculum learning regime with Fourier domain amplitude fusion in the testing time rather than in the training time like this work and most other existing domain adaptation works